Discovering Retroviruses: Beacons in the Biosphere

Author by : Anna Marie Skalka
Languange Used : en
Release Date : 2018-10-22
Publisher by : Harvard University Press

ISBN :

Description : Eight percent of our DNA contains retroviruses that are millions of years old. Anna Marie Skalka explains how our evolving knowledge of these particles has advanced genetic engineering, gene delivery systems, and precision medicine. Retroviruses cause disease but also hold clues to prevention and treatment possibilities that are anything but retro....

Author by : Jane Flint
Languange Used : en
Release Date : 2020-08-07
Publisher by : John Wiley & Sons

ISBN :

Description : Principles of Virology, the leading virology textbook in use, is an extremely valuable and highly informative presentation of virology at the interface of modern cell biology and immunology. This text utilizes a uniquely rational approach by highlighting common principles and processes across all viruses. Using a set of representative viruses to illustrate the breadth of viral complexity, students are able to understand viral reproduction and pathogenesis and are equipped with the necessary tools for future encounters with new or understudied viruses. This fifth edition was updated to keep pace with the ever-changing field of virology. In addition to the beloved full-color illustrations, video interviews with leading scientists, movies, and links to exciting blogposts on relevant topics, this edition includes study questions and active learning puzzles in each chapter, as well as short descriptions regarding the key messages of references of special interest. Volume I: Molecular Biology focuses on the molecular processes of viral reproduction, from entry through release. Volume II: Pathogenesis and Control addresses the interplay between viruses and their host organisms, on both the micro- and macroscale, including chapters on public health, the immune response, vaccines and other antiviral strategies, viral evolution, and a brand new chapter on the therapeutic uses of viruses. These two volumes can be used for separate courses or together in a single course. Each includes a unique appendix, glossary, and links to internet resources. Principles of Virology, Fifth Edition, is ideal for teaching the strategies by which all viruses reproduce, spread within a host, and are maintained within populations. This edition carefully reflects the results of extensive vetting and feedback received from course instructors and students, making this renowned textbook even more appropriate for undergraduate and graduate courses in virology, microbiology, and infectious diseases....

Author by : S. Jane Flint
Languange Used : en
Release Date : 2020-08-03
Publisher by : John Wiley & Sons

ISBN :

Description : Principles of Virology, the leading virology textbook in use, is an extremely valuable and highly informative presentation of virology at the interface of modern cell biology and immunology. This text utilizes a uniquely rational approach by highlighting common principles and processes across all viruses. Using a set of representative viruses to illustrate the breadth of viral complexity, students are able to under-stand viral reproduction and pathogenesis and are equipped with the necessary tools for future encounters with new or understudied viruses. This fifth edition was updated to keep pace with the ever-changing field of virology. In addition to the beloved full-color illustrations, video interviews with leading scientists, movies, and links to exciting blogposts on relevant topics, this edition includes study questions and active learning puzzles in each chapter, as well as short descriptions regarding the key messages of references of special interest. Volume I: Molecular Biology focuses on the molecular processes of viral reproduction, from entry through release. Volume II: Pathogenesis and Control addresses the interplay between viruses and their host organisms, on both the micro- and macroscale, including chapters on public health, the immune response, vaccines and other antiviral strategies, viral evolution, and a brand new chapter on the therapeutic uses of viruses. These two volumes can be used for separate courses or together in a single course. Each includes a unique appendix, glossary, and links to internet resources. Principles of Virology, Fifth Edition, is ideal for teaching the strategies by which all viruses reproduce, spread within a host, and are maintained within populations. This edition carefully reflects the results of extensive vetting and feedback received from course instructors and students, making this renowned textbook even more appropriate for undergraduate and graduate courses in virology, microbiology, and infectious diseases....

Author by : Neeraja Sankaran
Languange Used : en
Release Date : 2021-03-30
Publisher by : University of Pittsburgh Press

ISBN :

Description : In 1965, French microbiologist André Lwoff was awarded the Nobel Prize in Physiology or Medicine for his work on lysogeny—one of the two types of viral life cycles—which resolved a contentious debate among scientists about the nature of viruses. A Tale of Two Viruses is the first study of medical virology to compare the history of two groups of medically important viruses—bacteriophages, which infect bacteria, and sarcoma agents, which cause cancer—and the importance of Lwoff’s discovery to our modern understanding of what a virus is. Although these two groups of viruses may at first glance appear to have little in common, they share uniquely parallel histories. The lysogenic cycle, unlike the lytic, enables viruses to replicate in the host cell without destroying it and to remain dormant in a cell’s genetic material indefinitely, or until induced by UV radiation. But until Lwoff’s discovery of the mechanism of lysogeny, microbiologist Félix d’Herelle and pathologist Peyton Rous, who themselves first discovered and argued for the viral identity of bacteriophages and certain types of cancer, respectively, faced opposition from contemporary researchers who would not accept their findings. By following the research trajectories of the two virus groups, Sankaran takes a novel approach to the history of the development of the field of medical virology, considering both the flux in scientific concepts over time and the broader scientific landscapes or styles that shaped those ideas and practices....

Author by : Gregory J. Morgan
Languange Used : en
Release Date : 2022-08-02
Publisher by : JHU Press

ISBN :

Description : "The author tells a history of the study of cancer-causing viruses from the early twentieth century to the development of an HPV vaccine for cervical cancer in 2006. He profiles the "cancer virus hunters" who made breakthroughs in tumor virology"--...

Author by : Joseph P. Byrne
Languange Used : en
Release Date : 2021-01-27
Publisher by : Bloomsbury Publishing USA

ISBN :

Description : Beyond their impact on public health, epidemics shape and are shaped by political, economic, and social forces. This book examines these connections, exploring key topics in the study of disease outbreaks and delving deep into specific historical and contemporary examples. From the Black Death that ravaged Europe in the 14th century to the influenza pandemic following World War I and the novel strain of coronavirus that made "social distancing" the new normal, wide-scale disease outbreaks have played an important role throughout human history. In addition to the toll they take on human lives, epidemics have spurred medical innovations, toppled governments, crippled economies, and led to cultural revolutions. Epidemics and Pandemics: From Ancient Plagues to Modern-Day Threats provides readers with a holistic view of the terrifying—and fascinating—topic of epidemics and pandemics. In Volume 1, readers will discover what an epidemic is, how it emerges and spreads, what diseases are most likely to become epidemics, and how disease outbreaks are tracked, prevented, and combatted. They will learn about the impacts of such modern factors as global air travel and antibiotic resistance, as well as the roles played by public health agencies and the media. Volume 2 offers detailed case studies that explore the course and lasting significance of individual epidemics and pandemics throughout history....

Author by : Siddhartha Mukherjee
Languange Used : de
Release Date : 2022-06-30
Publisher by : Ullstein Buchverlage

ISBN :

Description : »Eine grandiose Kulturgeschichte des Krebses.« SPIEGEL Krebs ist ein Überlebenskünstler: Er verändert sich, er passt sich an, er entwickelt sich weiter, er wächst. Er ist uns biologisch so nahe, dass wir uns oft selbst zerstören, wenn wir ihn vernichten. Die Suche nach der »Heilung« von Krebs hat sich allmählich zum Maßstab unseres wissenschaftlichen und medizinischen Fortschritts entwickelt. In seinem bahnbrechenden und preisgekrönten Buch erzählt der renommierte Onkologe Siddhartha Mukherjee die faszinierende Geschichte der Beziehung zwischen Mensch und Krebs. Wie haben wir ihn uns in der Vergangenheit vorgestellt? Was konnten wir ihm entgegensetzen? Wo stehen wir jetzt im Kampf gegen diese gefräßigste aller Krankheiten? Mukherjee zeigt, wie weit wir bei der Lösung eines der großen Rätsel der Wissenschaft gekommen sind, und gibt einen faszinierenden Ausblick auf unsere zukünftigen Fortschritte. »Eine brillante Kombination aus Medizin-Krimi und Kriegsgeschichte. Ein Jahrhundertbuch.« STERN »Ein ganz wunderbares Buch. Nicht nur, weil es so spannend, so elegant, so ungeheuer reich an Wissen ist. Sondern vor allem, weil es auch von der Hoffnung erzählt.« WAMS...